3F2O

Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) in complex with a 20-residue VASA peptide

Summary for 3F2O

• Entry DOI: 10.2210/pdb3f2o/pdb
• Descriptor: SPRY domain-containing SOCS box protein 1, 20-mer peptide from ATP-dependent RNA helicase vasa (3 entities in total)
• Functional Keywords: apoptosis, nucleus, transcription regulation, sgc, structural genomics consortium, phosphoprotein, ubl conjugation pathway, atp-binding, developmental protein, differentiation, helicase, hydrolase, nucleotide-binding, oogenesis, apoptosis-hydrolase complex, apoptosis/hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm (Probable): Q96BD6; Cytoplasm: P09052
• Total number of polymer chains: 4
• Total formula weight: 58057.24

Authors

Filippakopoulos, P.,Sharpe, T.,Keates, T.,Murray, J.W.,Savitsky, P.,Roos, A.,Pike, A.C.W.,Von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (deposition date: 2008-10-30, release date: 2008-12-09, Last modification date: 2023-11-01)

• Primary citation: Filippakopoulos, P.,Low, A.,Sharpe, T.D.,Uppenberg, J.,Yao, S.,Kuang, Z.,Savitsky, P.,Lewis, R.S.,Nicholson, S.E.,Norton, R.S.,Bullock, A.N.; Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.; J.Mol.Biol., 401:389-402, 2010; PubMed: 20561531; DOI: 10.1016/j.jmb.2010.06.017

Experimental method

X-RAY DIFFRACTION (2.05 Å)