3EX7

The crystal structure of EJC in its transition state

Summary for 3EX7

• Entry DOI: 10.2210/pdb3ex7/pdb
• Related: 2HXY 2HYI
• Descriptor: Protein mago nashi homolog, RNA-binding protein 8A, Eukaryotic initiation factor 4A-III, ... (9 entities in total)
• Functional Keywords: protein-rna complex, mrna processing, mrna splicing, mrna transport, nonsense-mediated mrna decay, nucleus, rna-binding, spliceosome, transport, alternative splicing, cytoplasm, phosphoprotein, acetylation, atp-binding, helicase, hydrolase, nucleotide-binding, rrna processing, coiled coil, hydrolase-rna binding protein-rna complex, hydrolase/rna binding protein/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P61326 Q9Y5S9 P38919; Cytoplasm, perinuclear region: O15234
• Total number of polymer chains: 10
• Total formula weight: 197205.24

Authors

Andersen, G.R.,Nielsen, K.H. (deposition date: 2008-10-16, release date: 2008-12-09, Last modification date: 2023-11-01)

• Primary citation: Nielsen, K.H.,Chamieh, H.,Andersen, C.B.,Fredslund, F.,Hamborg, K.,Le Hir, H.,Andersen, G.R.; Mechanism of ATP turnover inhibition in the EJC; Rna, 15:67-75, 2009; PubMed: 19033377; DOI: 10.1261/rna.1283109

Experimental method

X-RAY DIFFRACTION (2.301 Å)