3EUU

Crystal structure of the FGFR2 D2 domain

Summary for 3EUU

• Entry DOI: 10.2210/pdb3euu/pdb
• Related: 3CAF
• Descriptor: Fibroblast growth factor receptor 2 (2 entities in total)
• Functional Keywords: ig-like, alternative splicing, atp-binding, cell membrane, craniosynostosis, disease mutation, ectodermal dysplasia, glycoprotein, heparin-binding, immunoglobulin domain, kinase, lacrimo-auriculo-dento-digital syndrome, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, secreted, transferase, transmembrane, tyrosine-protein kinase
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane; Single-pass type I membrane protein. Isoform 14: Secreted. Isoform 19: Secreted: P21802
• Total number of polymer chains: 2
• Total formula weight: 23216.52

Authors

Sakon, J.,Guo, F.,Dakshinamurthy, R.,Kathir, K.M.,Thallapuranam, S.K.K. (deposition date: 2008-10-10, release date: 2009-08-25, Last modification date: 2023-09-06)

• Primary citation: Guo, F.,Dakshinamurthy, R.,Kathir, K.M.,Thallapuranam, S.K.K.,Sakon, J.; Crystal structure of the D2 domain of hFGFR2; To be Published,

Experimental method

X-RAY DIFFRACTION (2.34 Å)