3EQT
Crystal structure of human LGP2 C-terminal domain in complex with dsRNA
Summary for 3EQT
Entry DOI | 10.2210/pdb3eqt/pdb |
Descriptor | ATP-dependent RNA helicase DHX58, 5'-R(*GP*CP*GP*CP*GP*CP*GP*C)-3', ZINC ION, ... (4 entities in total) |
Functional Keywords | innate immunity, rig-i-like helicases, viral rna detection, lgp2-dsrna complex, atp-binding, coiled coil, cytoplasm, helicase, hydrolase, immune response, nucleotide-binding, polymorphism, rna-binding, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: Q96C10 |
Total number of polymer chains | 4 |
Total formula weight | 38682.36 |
Authors | |
Primary citation | Li, X.,Ranjith-Kumar, C.T.,Brooks, M.T.,Dharmaiah, S.,Herr, A.B.,Kao, C.,Li, P. The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA J.Biol.Chem., 284:13881-13891, 2009 Cited by PubMed: 19278996DOI: 10.1074/jbc.M900818200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report