3ENM
The structure of the MAP2K MEK6 reveals an autoinhibitory dimer
Summary for 3ENM
Entry DOI | 10.2210/pdb3enm/pdb |
Descriptor | Dual specificity mitogen-activated protein kinase kinase 6, SULFATE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | mek6, autoinhibited dimer, atp-binding, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, tyrosine-protein kinase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 147194.66 |
Authors | Min, X.,Akella, R.,He, H.,Humphreys, J.M.,Tsutakawa, S.,Lee, S.-J.,Tainer, J.A.,Cobb, M.H.,Goldsmith, E.J. (deposition date: 2008-09-25, release date: 2009-03-03, Last modification date: 2021-10-20) |
Primary citation | Min, X.,Akella, R.,He, H.,Humphreys, J.M.,Tsutakawa, S.E.,Lee, S.J.,Tainer, J.A.,Cobb, M.H.,Goldsmith, E.J. The structure of the MAP2K MEK6 reveals an autoinhibitory dimer Structure, 17:96-104, 2009 Cited by PubMed: 19141286DOI: 10.1016/j.str.2008.11.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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