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3ENM

The structure of the MAP2K MEK6 reveals an autoinhibitory dimer

Summary for 3ENM
Entry DOI10.2210/pdb3enm/pdb
DescriptorDual specificity mitogen-activated protein kinase kinase 6, SULFATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywordsmek6, autoinhibited dimer, atp-binding, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, tyrosine-protein kinase
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight147194.66
Authors
Min, X.,Akella, R.,He, H.,Humphreys, J.M.,Tsutakawa, S.,Lee, S.-J.,Tainer, J.A.,Cobb, M.H.,Goldsmith, E.J. (deposition date: 2008-09-25, release date: 2009-03-03, Last modification date: 2021-10-20)
Primary citationMin, X.,Akella, R.,He, H.,Humphreys, J.M.,Tsutakawa, S.E.,Lee, S.J.,Tainer, J.A.,Cobb, M.H.,Goldsmith, E.J.
The structure of the MAP2K MEK6 reveals an autoinhibitory dimer
Structure, 17:96-104, 2009
Cited by
PubMed: 19141286
DOI: 10.1016/j.str.2008.11.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.35 Å)
Structure validation

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