3E6Y

Structure of 14-3-3 in complex with the differentiation-inducing agent Cotylenin A

Summary for 3E6Y

Entry DOI	10.2210/pdb3e6y/pdb
Descriptor	14-3-3-like protein C, H+-ATPase phosphopeptide QSYpTV, Cotylenin A, ... (5 entities in total)
Functional Keywords	adapter protein, signaling protein
Biological source	Nicotiana tabacum (American tobacco,tobacco) More
Total number of polymer chains	4
Total formula weight	61494.17
Authors	Ottmann, C.,Weyand, M.,Wittinghofer, A.,Oecking, C. (deposition date: 2008-08-17, release date: 2009-03-10, Last modification date: 2023-08-30)
Primary citation	Ottmann, C.,Weyand, M.,Sassa, T.,Inoue, T.,Kato, N.,Wittinghofer, A.,Oecking, C. A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A J.Mol.Biol., 386:913-919, 2009 Cited by PubMed: 19244612 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation