3E3Q

Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9

Summary for 3E3Q

• Entry DOI: 10.2210/pdb3e3q/pdb
• Related: 2E7L 2OI9 3E2H
• Descriptor: H-2 class I histocompatibility antigen, L-D alpha chain, QL9 peptide, T-cell receptor alpha chain V region PHDS58, ... (4 entities in total)
• Functional Keywords: tcr, mhc, high affinity, cross reactivity, glycoprotein, immune response, membrane, mhc i, phosphoprotein, transmembrane, immunoglobulin domain, receptor, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01897
• Total number of polymer chains: 32
• Total formula weight: 365724.38

Authors

Colf, L.A.,Garcia, K.C. (deposition date: 2008-08-07, release date: 2008-11-04, Last modification date: 2023-08-30)

• Primary citation: Jones, L.L.,Colf, L.A.,Stone, J.D.,Garcia, K.C.,Kranz, D.M.; Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation.; J.Immunol., 181:6255-6264, 2008; PubMed: 18941216

Experimental method

X-RAY DIFFRACTION (2.95 Å)