3DXK

Structure of Bos Taurus Arp2/3 Complex with Bound Inhibitor CK0944636

Summary for 3DXK

• Entry DOI: 10.2210/pdb3dxk/pdb
• Related: 3DXM
• Descriptor: Actin-related protein 3, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... (9 entities in total)
• Functional Keywords: beta-propeller, acetylation, actin-binding, atp-binding, cell projection, cytoplasm, cytoskeleton, nucleotide-binding, phosphoprotein, wd repeat, structural protein
• Biological source: Bos taurus; More
• Cellular location: Cytoplasm, cytoskeleton (By similarity): P61157 A7MB62 Q58CQ2 Q3MHR7 Q3T035 Q148J6 Q3SYX9
• Total number of polymer chains: 7
• Total formula weight: 224484.95

Authors

Nolen, B.J.,Tomasevic, N.,Russell, A.,Pierce, D.W.,Jia, Z.,Hartman, J.,Sakowicz, R.,Pollard, T.D. (deposition date: 2008-07-24, release date: 2009-07-28, Last modification date: 2023-08-30)

• Primary citation: Nolen, B.J.,Tomasevic, N.,Russell, A.,Pierce, D.W.,Jia, Z.,McCormick, C.D.,Hartman, J.,Sakowicz, R.,Pollard, T.D.; Characterization of two classes of small molecule inhibitors of Arp2/3 complex; Nature, 460:1031-1034, 2009; PubMed: 19648907; DOI: 10.1038/nature08231

Experimental method

X-RAY DIFFRACTION (2.7 Å)