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3DWY

Crystal Structure of the Bromodomain of Human CREBBP

Summary for 3DWY
Entry DOI10.2210/pdb3dwy/pdb
DescriptorCREB-binding protein, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywordsbromodomain, creb binding protein, structural genomics consortium, sgc, activator, disease mutation, host-virus interaction, metal-binding, methylation, nucleus, phosphoprotein, transcription, transcription regulation, transferase, zinc-finger
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm: Q92793
Total number of polymer chains2
Total formula weight28632.90
Authors
Primary citationFilippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.
Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149:214-231, 2012
Cited by
PubMed: 22464331
DOI: 10.1016/j.cell.2012.02.013
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.98 Å)
Structure validation

217705

건을2024-03-27부터공개중

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