3DLQ

Crystal structure of the IL-22/IL-22R1 complex

Summary for 3DLQ

Entry DOI	10.2210/pdb3dlq/pdb
Descriptor	Interleukin-22, Interleukin-22 receptor subunit alpha-1 (3 entities in total)
Functional Keywords	cytokine-receptor complex, fibronectin-iii, cytokine, glycoprotein, polymorphism, secreted, membrane, receptor, transmembrane, cytokine-cytokine receptor complex, cytokine/cytokine receptor
Biological source	Homo sapiens (Human) More
Cellular location	Secreted: Q9GZX6 Membrane; Single-pass type I membrane protein: Q8N6P7
Total number of polymer chains	2
Total formula weight	41278.04
Authors	Bleicher, L.,de Moura, P.R.,Watanabe, L.,Colau, D.,Dumoutier, L.,Renauld, J.-C.,Polikarpov, I. (deposition date: 2008-06-28, release date: 2008-08-19, Last modification date: 2023-11-01)
Primary citation	Bleicher, L.,de Moura, P.R.,Watanabe, L.,Colau, D.,Dumoutier, L.,Renauld, J.-C.,Polikarpov, I. Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism Febs Lett., 582:2985-2992, 2008 Cited by PubMed: 18675809 DOI: 10.1016/j.febslet.2008.07.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation