3DJY

Nonaged Form of Human Butyrylcholinesterase Inhibited by Tabun

Summary for 3DJY

Entry DOI	10.2210/pdb3djy/pdb
Related	3DKK 3DL4 3DL7
Descriptor	Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	hydrolase, tabun, organophosphate, aging, disease mutation, glycoprotein, serine esterase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	62209.53
Authors	Carletti, E.,Nachon, F. (deposition date: 2008-06-24, release date: 2008-12-02, Last modification date: 2021-10-20)
Primary citation	Carletti, E.,Li, H.,Li, B.,Ekstrom, F.,Nicolet, Y.,Loiodice, M.,Gillon, E.,Froment, M.T.,Lockridge, O.,Schopfer, L.M.,Masson, P.,Nachon, F. Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation. J.Am.Chem.Soc., 130:16011-16020, 2008 Cited by PubMed: 18975951 DOI: 10.1021/ja804941z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation