3DGC

Structure of IL-22/IL-22R1

Summary for 3DGC

Entry DOI	10.2210/pdb3dgc/pdb
Descriptor	Interleukin-22, Interleukin-22 receptor subunit alpha-1, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	il-22, il-22r1, cytokine, receptor, signaling molecule, glycoprotein, secreted, membrane, transmembrane, cytokine-signaling protein complex, cytokine/signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Secreted: Q9GZX6 Membrane; Single-pass type I membrane protein: Q9HB22
Total number of polymer chains	4
Total formula weight	84609.62
Authors	Jones, B.C.,Logsdon, N.J.,Walter, M.R. (deposition date: 2008-06-13, release date: 2008-07-15, Last modification date: 2020-07-29)
Primary citation	Jones, B.C.,Logsdon, N.J.,Walter, M.R. Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain. Structure, 16:1333-1344, 2008 Cited by PubMed: 18599299 DOI: 10.1016/j.str.2008.06.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation