3D7U

Structural basis for the recognition of c-Src by its inactivator Csk

Summary for 3D7U

Entry DOI	10.2210/pdb3d7u/pdb
Related	3D7T
Descriptor	Tyrosine-protein kinase CSK, Proto-oncogene tyrosine-protein kinase Src (2 entities in total)
Functional Keywords	csk c-src tyrosine kinase, atp-binding, kinase, membrane, nucleotide-binding, phosphoprotein, sh2 domain, sh3 domain, transferase, tyrosine-protein kinase, lipoprotein, myristate, proto-oncogene
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm (By similarity): P41240 Cell membrane (By similarity): P00523
Total number of polymer chains	4
Total formula weight	122851.72
Authors	Levinson, N.M.,Seeliger, M.A.,Cole, P.A.,Kuriyan, J. (deposition date: 2008-05-21, release date: 2008-08-05, Last modification date: 2024-02-21)
Primary citation	Levinson, N.M.,Seeliger, M.A.,Cole, P.A.,Kuriyan, J. Structural basis for the recognition of c-Src by its inactivator Csk. Cell(Cambridge,Mass.), 134:124-134, 2008 Cited by PubMed: 18614016 DOI: 10.1016/j.cell.2008.05.051 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.111 Å)

Structure validation