3D7T
Structural basis for the recognition of c-Src by its inactivator Csk
Summary for 3D7T
Entry DOI | 10.2210/pdb3d7t/pdb |
Related | 3D7U |
Descriptor | Tyrosine-protein kinase CSK, Proto-oncogene tyrosine-protein kinase Src, STAUROSPORINE (3 entities in total) |
Functional Keywords | csk src tyrosine kinase, atp-binding, cytoplasm, kinase, membrane, nucleotide-binding, phosphoprotein, polymorphism, sh2 domain, sh3 domain, transferase, tyrosine-protein kinase, alternative splicing, lipoprotein, myristate, proto-oncogene |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (By similarity): P41240 Cell membrane (By similarity): P00523 |
Total number of polymer chains | 2 |
Total formula weight | 63636.27 |
Authors | Levinson, N.M.,Seeliger, M.A.,Cole, P.A.,Kuriyan, J. (deposition date: 2008-05-21, release date: 2008-08-05, Last modification date: 2021-10-20) |
Primary citation | Levinson, N.M.,Seeliger, M.A.,Cole, P.A.,Kuriyan, J. Structural basis for the recognition of c-Src by its inactivator Csk. Cell(Cambridge,Mass.), 134:124-134, 2008 Cited by PubMed: 18614016DOI: 10.1016/j.cell.2008.05.051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.899 Å) |
Structure validation
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