3D7B

The Ribonuclease A- 5'-Deoxy-5'-N-pyrrolidinouridine complex

Summary for 3D7B

Entry DOI	10.2210/pdb3d7b/pdb
Related	3D6O 3D6P 3D6Q
Descriptor	Ribonuclease pancreatic, CITRATE ANION, 1-(5-deoxy-5-pyrrolidin-1-yl-alpha-L-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione, ... (4 entities in total)
Functional Keywords	hydrolase, ribonuclease a, ligand, endonuclease, glycation, glycoprotein, nuclease, secreted
Biological source	Bos taurus (bovine)
Cellular location	Secreted: P61823
Total number of polymer chains	2
Total formula weight	28092.16
Authors	Leonidas, D.D.,Zographos, S.E.,Oikonomakos, N.G. (deposition date: 2008-05-21, release date: 2009-02-10, Last modification date: 2023-08-30)
Primary citation	Samanta, A.,Leonidas, D.D.,Dasgupta, S.,Pathak, T.,Zographos, S.E.,Oikonomakos, N.G. Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation. J.Med.Chem., 52:932-942, 2009 Cited by PubMed: 19173562 DOI: 10.1021/jm800724t PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation