3D4U

Bovine thrombin-activatable fibrinolysis inhibitor (TAFIa) in complex with tick-derived carboxypeptidase inhibitor.

Summary for 3D4U

Entry DOI	10.2210/pdb3d4u/pdb
Related	1KWM 1ZLI
Descriptor	Carboxypeptidase B2, Carboxypeptidase inhibitor, ZINC ION, ... (6 entities in total)
Functional Keywords	protease-inhibitor complex, carboxypeptidase, glycoprotein, hydrolase, metal-binding, metalloprotease, protease, secreted, zymogen, blood coagulation, fibrinolysis, metalloenzyme inhibitor, metalloprotease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Rhipicephalus bursa More
Cellular location	Secreted (By similarity): Q2KIG3 Secreted: Q5EPH2
Total number of polymer chains	2
Total formula weight	44500.68
Authors	Sanglas, L.,Valnickova, Z.,Arolas, J.L.,Pallares, I.,Guevara, T.,Sola, M.,Kristensen, T.,Enghild, J.J.,Aviles, F.X.,Gomis-Ruth, F.X. (deposition date: 2008-05-15, release date: 2008-08-19, Last modification date: 2023-11-01)
Primary citation	Sanglas, L.,Valnickova, Z.,Arolas, J.L.,Pallares, I.,Guevara, T.,Sola, M.,Kristensen, T.,Enghild, J.J.,Aviles, F.X.,Gomis-Ruth, F.X. Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis. Mol.Cell, 31:598-606, 2008 Cited by PubMed: 18722183 DOI: 10.1016/j.molcel.2008.05.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation