3D0H

Crystal structure of spike protein receptor-binding domain from the 2002-2003 SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2

Summary for 3D0H

• Entry DOI: 10.2210/pdb3d0h/pdb
• Related: 2AJF 3D0G 3D0I
• Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: sars coronavirus, spike protein, receptor-binding domain, rbd, angiotensin-converting enzyme 2, ace2, virus-host interface, host adaptation, cross-species infections, human, palm civet, carboxypeptidase, chloride, glycoprotein, hydrolase, membrane, metal-binding, metalloprotease, protease, secreted, transmembrane, envelope protein, host-virus interaction, lipoprotein, palmitate, virion, virulence
• Biological source: Paguma larvata (Masked palm civet); More
• Total number of polymer chains: 4
• Total formula weight: 180524.01

Authors

Li, F. (deposition date: 2008-05-01, release date: 2008-07-08, Last modification date: 2020-07-29)

• Primary citation: Li, F.; Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections; J.Virol., 82:6984-6991, 2008; PubMed: 18448527; DOI: 10.1128/JVI.00442-08

Experimental method

X-RAY DIFFRACTION (3.1 Å)