Summary for 4NKQ
| Entry DOI | 10.2210/pdb4nkq/pdb |
| Related | 3cxe |
| Descriptor | Cytokine receptor common subunit beta, Granulocyte-macrophage colony-stimulating factor, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, ... (4 entities in total) |
| Functional Keywords | gm-csf, receptor complex, dodecamer, disease mutation, glycoprotein, membrane, phosphoprotein, transmembrane, cytokine, growth factor, secreted, cytokine-cytokine receptor complex, cytokine/cytokine receptor |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 97486.58 |
| Authors | Parker, M.W.,Broughton, S.E. (deposition date: 2013-11-13, release date: 2015-09-23, Last modification date: 2020-07-29) |
| Primary citation | Broughton, S.E.,Hercus, T.R.,Nero, T.L.,Dottore, M.,McClure, B.J.,Dhagat, U.,Taing, H.,Gorman, M.A.,King-Scott, J.,Lopez, A.F.,Parker, M.W. Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure, 24:1271-1281, 2016 Cited by PubMed: 27396825DOI: 10.1016/j.str.2016.05.017 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.301 Å) |
Structure validation
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