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3CR0

Wee1 kinase complex with inhibitor PD259_809

Summary for 3CR0
Entry DOI10.2210/pdb3cr0/pdb
Related1X8B
DescriptorWee1-like protein kinase, CHLORIDE ION, 4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione, ... (5 entities in total)
Functional Keywordskinase domain, inhibitor complex, transferase
Biological sourceHomo sapiens
Cellular locationNucleus: P30291
Total number of polymer chains1
Total formula weight32779.10
Authors
Squire, C.J.,Baker, E.N. (deposition date: 2008-04-03, release date: 2009-02-24, Last modification date: 2023-11-01)
Primary citationSquire, C.J.,Baker, E.N.,Dickson, J.M.,Ivanovic, I.,Smaill, J.,Denny, W.A.,Palmer, B.,Thompson, A.
Structural determinants of Wee1 inhibitor selectivity
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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