3CQE

Wee1 kinase complex with inhibitor PD074291

Summary for 3CQE

• Entry DOI: 10.2210/pdb3cqe/pdb
• Related: 1X8B
• Descriptor: Wee1-like protein kinase, CHLORIDE ION, 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide, ... (5 entities in total)
• Functional Keywords: kinase domain, inhibitor, transferase
• Biological source: Homo sapiens
• Cellular location: Nucleus: P30291
• Total number of polymer chains: 1
• Total formula weight: 32901.03

Authors

Squire, C.J.,Baker, E.N. (deposition date: 2008-04-02, release date: 2009-02-24, Last modification date: 2023-11-01)

• Primary citation: Squire, C.J.,Baker, E.N.,Dickson, J.M.,Ivanovic, I.,Smaill, J.,Denny, W.A.,Palmer, B.,Thompson, A.; Structural Determinants of Wee1 Inhibitor Selectivity; To be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)