3CPH

Crystal structure of Sec4 in complex with Rab-GDI

Summary for 3CPH

• Entry DOI: 10.2210/pdb3cph/pdb
• Related: 3CPI 3CPJ
• Descriptor: Rab GDP-dissociation inhibitor, Ras-related protein SEC4, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: rab gtpase, prenylation, vesicular transport, cytoplasm, cytoplasmic vesicle, exocytosis, gtp-binding, lipoprotein, membrane, nucleotide-binding, palmitate, phosphoprotein, protein transport, gtpase activation
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Cellular location: Cytoplasmic vesicle, secretory vesicle membrane; Lipid-anchor; Cytoplasmic side: P39958; Cytoplasm: P07560
• Total number of polymer chains: 3
• Total formula weight: 126336.36

Authors

Kravchenko, S.,Ignatev, A.,Goody, R.S.,Rak, A.,Pylypenko, O. (deposition date: 2008-03-31, release date: 2008-05-06, Last modification date: 2023-11-01)

• Primary citation: Ignatev, A.,Kravchenko, S.,Rak, A.,Goody, R.S.,Pylypenko, O.; A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism.; J.Biol.Chem., 283:18377-18384, 2008; PubMed: 18426803; DOI: 10.1074/jbc.M709718200

Experimental method

X-RAY DIFFRACTION (2.9 Å)