3CN4

Human transthyretin (TTR) in complex with N-(3,5-Dibromo-4-hydroxyphenyl)benzamide

Summary for 3CN4

Entry DOI	10.2210/pdb3cn4/pdb
Related	2QGB 3CN0 3CN1 3CN2 3CN3
Descriptor	Transthyretin, N-(3,5-dibromo-4-hydroxyphenyl)benzamide (3 entities in total)
Functional Keywords	transthyretin, tetramer, hormone, transport protein
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	28296.77
Authors	Connelly, S.,Wilson, I.A. (deposition date: 2008-03-24, release date: 2008-10-28, Last modification date: 2024-02-21)
Primary citation	Johnson, S.M.,Connelly, S.,Wilson, I.A.,Kelly, J.W. Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies. J.Med.Chem., 51:6348-6358, 2008 Cited by PubMed: 18811132 DOI: 10.1021/jm800435s PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation