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3CL3

Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome

Summary for 3CL3
Entry DOI10.2210/pdb3cl3/pdb
DescriptorORF K13, NF-kappa-B essential modulator (2 entities in total)
Functional Keywordsdeath effector domain, coiled-coil, coiled coil, cytoplasm, disease mutation, ectodermal dysplasia, host-virus interaction, nucleus, transcription, transcription regulation, viral protein-signaling protein complex, viral protein/signaling protein
Biological sourceHuman gammaherpesvirus 8
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Total number of polymer chains4
Total formula weight70846.87
Authors
Bagneris, C.,Ageichik, A.V.,Cronin, N.,Boshoff, C.,Waksman, G.,Barrett, T. (deposition date: 2008-03-18, release date: 2008-06-17, Last modification date: 2024-02-21)
Primary citationBagneris, C.,Ageichik, A.V.,Cronin, N.,Wallace, B.,Collins, M.,Boshoff, C.,Waksman, G.,Barrett, T.
Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome.
Mol.Cell, 30:620-631, 2008
Cited by
PubMed: 18538660
DOI: 10.1016/j.molcel.2008.04.029
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

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