3CIY

Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA

3CIY の概要

• エントリーDOI: 10.2210/pdb3ciy/pdb
• 関連するPDBエントリー: 2A0Z 3CIG
• 分子名称: 46-MER, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• 機能のキーワード: leucine rich repeat, lrr, protein-dsrna complex, innate immunity, tlr, dsrna, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, immune system-rna complex, immune system/rna
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 197440.27

構造登録者

Liu, L.,Botos, I.,Wang, Y.,Leonard, J.N.,Shiloach, J.,Segal, D.M.,Davies, D.R. (登録日: 2008-03-12, 公開日: 2008-05-06, 最終更新日: 2023-08-30)

• 主引用文献: Liu, L.,Botos, I.,Wang, Y.,Leonard, J.N.,Shiloach, J.,Segal, D.M.,Davies, D.R.; Structural basis of toll-like receptor 3 signaling with double-stranded RNA.; Science, 320:379-381, 2008; PubMed: 18420935; DOI: 10.1126/science.1155406

実験手法

X-RAY DIFFRACTION (3.41 Å)