3CIY

Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA

Summary for 3CIY

Entry DOI	10.2210/pdb3ciy/pdb
Related	2A0Z 3CIG
Descriptor	46-MER, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
Functional Keywords	leucine rich repeat, lrr, protein-dsrna complex, innate immunity, tlr, dsrna, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, immune system-rna complex, immune system/rna
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	4
Total formula weight	197440.27
Authors	Liu, L.,Botos, I.,Wang, Y.,Leonard, J.N.,Shiloach, J.,Segal, D.M.,Davies, D.R. (deposition date: 2008-03-12, release date: 2008-05-06, Last modification date: 2023-08-30)
Primary citation	Liu, L.,Botos, I.,Wang, Y.,Leonard, J.N.,Shiloach, J.,Segal, D.M.,Davies, D.R. Structural basis of toll-like receptor 3 signaling with double-stranded RNA. Science, 320:379-381, 2008 Cited by PubMed: 18420935 DOI: 10.1126/science.1155406 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.41 Å)

Structure validation