3CII

Structure of NKG2A/CD94 bound to HLA-E

Summary for 3CII

Entry DOI	10.2210/pdb3cii/pdb
Descriptor	HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, HLA class I histocompatibility antigen peptide, ... (5 entities in total)
Functional Keywords	c-type lectin-like, glycoprotein, immune response, membrane, mhc i, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, lectin, receptor, signal-anchor, immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P13747 P17693 Secreted: P61769 Membrane; Single-pass type II membrane protein: Q13241 P26715
Total number of polymer chains	10
Total formula weight	145073.39
Authors	Strong, R.K.,Kaiser, B.K.,Pizarro, J.C. (deposition date: 2008-03-11, release date: 2008-05-13, Last modification date: 2023-08-30)
Primary citation	Kaiser, B.K.,Pizarro, J.C.,Kerns, J.,Strong, R.K. Structural basis for NKG2A/CD94 recognition of HLA-E. Proc.Natl.Acad.Sci.Usa, 105:6696-6701, 2008 Cited by PubMed: 18448674 DOI: 10.1073/pnas.0802736105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.41 Å)

Structure validation