3CIG

Crystal structure of mouse TLR3 ectodomain

Summary for 3CIG

• Entry DOI: 10.2210/pdb3cig/pdb
• Related: 3CIY
• Descriptor: Toll-like receptor 3, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: leucine-rich repeat, innate immunity, tlr, lrr, glycoprotein, immune response, inflammatory response, membrane, receptor, transmembrane, immune system
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 1
• Total formula weight: 84591.96

Authors

Liu, L.,Botos, I.,Wang, Y.,Leonard, J.N.,Shiloach, J.,Segal, D.M.,Davies, D.R. (deposition date: 2008-03-11, release date: 2008-05-06, Last modification date: 2023-08-30)

• Primary citation: Liu, L.,Botos, I.,Wang, Y.,Leonard, J.N.,Shiloach, J.,Segal, D.M.,Davies, D.R.; Structural basis of toll-like receptor 3 signaling with double-stranded RNA.; Science, 320:379-381, 2008; PubMed: 18420935; DOI: 10.1126/science.1155406

Experimental method

X-RAY DIFFRACTION (2.66 Å)