3CGY

Crystal Structure of Salmonella Sensor Kinase PhoQ catalytic domain in complex with radicicol

Summary for 3CGY

• Entry DOI: 10.2210/pdb3cgy/pdb
• Related: 3CGZ
• Descriptor: Virulence sensor histidine kinase phoQ, RADICICOL (2 entities in total)
• Functional Keywords: alpha-beta sandwich, bergerat fold, atp-binding, growth regulation, inner membrane, kinase, magnesium, membrane, metal-binding, nucleotide-binding, phosphoprotein, transferase, transmembrane, two-component regulatory system, virulence
• Biological source: Salmonella typhimurium
• Cellular location: Cell inner membrane; Multi-pass membrane protein (By similarity): P14147
• Total number of polymer chains: 3
• Total formula weight: 53182.04

Authors

Guarnieri, M.T.,Zhang, L.,Shen, J.,Zhao, R. (deposition date: 2008-03-06, release date: 2008-05-13, Last modification date: 2023-08-30)

• Primary citation: Guarnieri, M.T.,Zhang, L.,Shen, J.,Zhao, R.; The Hsp90 inhibitor radicicol interacts with the ATP-binding pocket of bacterial sensor kinase PhoQ.; J.Mol.Biol., 379:82-93, 2008; PubMed: 18440021; DOI: 10.1016/j.jmb.2008.03.036

Experimental method

X-RAY DIFFRACTION (2.6 Å)