3CF8

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with quercetin

Summary for 3CF8

• Entry DOI: 10.2210/pdb3cf8/pdb
• Related: 2GLL 3CF9 3D04
• Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ... (5 entities in total)
• Functional Keywords: fabz complex, quercetin, cytoplasm, lipid a biosynthesis, lipid synthesis, lyase
• Biological source: Helicobacter pylori
• Cellular location: Cytoplasm : Q5G940
• Total number of polymer chains: 6
• Total formula weight: 110774.82

Authors

Zhang, L.,Wu, D.,Liu, W.,Shen, X.,Jiang, H. (deposition date: 2008-03-03, release date: 2008-12-09, Last modification date: 2024-03-13)

• Primary citation: Zhang, L.,Kong, Y.,Wu, D.,Zhang, H.,Wu, J.,Chen, J.,Ding, J.,Hu, L.,Jiang, H.,Shen, X.; Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay; Protein Sci., 17:1971-1978, 2008; PubMed: 18780820; DOI: 10.1110/ps.036186.108

Experimental method

X-RAY DIFFRACTION (2.4 Å)