3CEG

Crystal structure of the UBC domain of baculoviral IAP repeat-containing protein 6

Summary for 3CEG

Entry DOI	10.2210/pdb3ceg/pdb
Descriptor	Baculoviral IAP repeat-containing protein 6 (2 entities in total)
Functional Keywords	apoptosis, ligase, protease inhibitor, thiol protease inhibitor, ubl conjugation pathway, structural genomics consortium, sgc
Biological source	Homo sapiens (human)
Cellular location	Golgi apparatus, trans-Golgi network membrane: Q9NR09
Total number of polymer chains	2
Total formula weight	74111.32
Authors	Walker, J.R.,Avvakumov, G.V.,Xue, S.,Butler-Cole, C.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2008-02-29, release date: 2008-04-01, Last modification date: 2012-11-28)
Primary citation	Sheng, Y.,Hong, J.H.,Doherty, R.,Srikumar, T.,Shloush, J.,Avvakumov, G.V.,Walker, J.R.,Xue, S.,Neculai, D.,Wan, J.W.,Kim, S.K.,Arrowsmith, C.H.,Raught, B.,Dhe-Paganon, S. A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11:329-341, 2012 Cited by PubMed: 22496338 DOI: 10.1074/mcp.O111.013706 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.008 Å)

Structure validation