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3CD2

LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COMPLEXES WITH FOLATE AND NADP+

Summary for 3CD2
Entry DOI10.2210/pdb3cd2/pdb
Related1CD2 2CD2 4CD2
DescriptorDIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, METHOTREXATE, ... (4 entities in total)
Functional Keywordsoxido-reductase, methotrexate, nadph, oxidoreductase
Biological sourcePneumocystis carinii
Total number of polymer chains1
Total formula weight25116.38
Authors
Cody, V.,Galitsky, N.,Rak, D.,Luft, J.,Pangborn, W.,Queener, S. (deposition date: 1999-03-16, release date: 2000-03-29, Last modification date: 2023-12-27)
Primary citationCody, V.,Galitsky, N.,Rak, D.,Luft, J.R.,Pangborn, W.,Queener, S.F.
Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+.
Biochemistry, 38:4303-4312, 1999
Cited by
PubMed: 10194348
DOI: 10.1021/bi982728m
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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