3CA7

High Resolution Crystal Structure of the EGF domain of Spitz

Summary for 3CA7

Entry DOI	10.2210/pdb3ca7/pdb
Descriptor	Protein spitz (2 entities in total)
Functional Keywords	spitz, argos, egf, developmental protein, differentiation, egf-like domain, endoplasmic reticulum, glycoprotein, golgi apparatus, membrane, neurogenesis, transmembrane, hormone-signaling protein complex, hormone/signaling protein
Biological source	Drosophila melanogaster (Fruit fly)
Cellular location	Cell membrane; Single-pass type I membrane protein: Q01083
Total number of polymer chains	1
Total formula weight	6012.86
Authors	Klein, D.E.,Stayrook, S.E.,Lemmon, M.A. (deposition date: 2008-02-19, release date: 2008-05-20, Last modification date: 2023-08-30)
Primary citation	Klein, D.E.,Stayrook, S.E.,Shi, F.,Narayan, K.,Lemmon, M.A. Structural basis for EGFR ligand sequestration by Argos. Nature, 453:1271-1275, 2008 Cited by PubMed: 18500331 DOI: 10.1038/nature06978 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation