3C13

Low pH-value crystal structure of emodin in complex with the catalytic subunit of protein kinase CK2

Summary for 3C13

Entry DOI	10.2210/pdb3c13/pdb
Related	1F0Q 1JWH 1LP4 1PJK 2PVR 2RKP 3BQC
Descriptor	Casein kinase II subunit alpha, CHLORIDE ION, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, ... (4 entities in total)
Functional Keywords	protein kinase ck2, casein kinase 2, eukaryotic protein kinases, emodin, atp-competitive inhibitor, atp-binding, nucleotide-binding, serine/threonine-protein kinase, transferase, wnt signaling pathway
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P68400
Total number of polymer chains	1
Total formula weight	40407.89
Authors	Niefind, K.,Raaf, J.,Issinger, O.-G. (deposition date: 2008-01-22, release date: 2008-02-12, Last modification date: 2023-11-01)
Primary citation	Raaf, J.,Klopffleisch, K.,Issinger, O.-G.,Niefind, K. The Catalytic Subunit of Human Protein Kinase CK2 Structurally Deviates from Its Maize Homologue in Complex with the Nucleotide Competitive Inhibitor Emodin J.Mol.Biol., 377:1-8, 2008 Cited by PubMed: 18242640 DOI: 10.1016/j.jmb.2008.01.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation