3BZH

Crystal structure of human ubiquitin-conjugating enzyme E2 E1

Summary for 3BZH

Entry DOI	10.2210/pdb3bzh/pdb
Descriptor	Ubiquitin-conjugating enzyme E2 E1, GLYCEROL (3 entities in total)
Functional Keywords	structural genomics consortium, ubiquitin, ubiquitin-conjugating enzyme, ligase, sgc, ubl conjugation pathway
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P51965
Total number of polymer chains	1
Total formula weight	21579.33
Authors	Walker, J.R.,Avvakumov, G.V.,Xue, S.,Li, Y.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2008-01-18, release date: 2008-02-26, Last modification date: 2023-08-30)
Primary citation	Sheng, Y.,Hong, J.H.,Doherty, R.,Srikumar, T.,Shloush, J.,Avvakumov, G.V.,Walker, J.R.,Xue, S.,Neculai, D.,Wan, J.W.,Kim, S.K.,Arrowsmith, C.H.,Raught, B.,Dhe-Paganon, S. A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11:329-341, 2012 Cited by PubMed: 22496338 DOI: 10.1074/mcp.O111.013706 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation