3BPT

Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin

Summary for 3BPT

• Entry DOI: 10.2210/pdb3bpt/pdb
• Descriptor: 3-hydroxyisobutyryl-CoA hydrolase, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, (2R)-3-HYDROXY-2-METHYLPROPANOIC ACID, ... (4 entities in total)
• Functional Keywords: coenzyme a, hydrolase, beta-hydroxyisobutyryl acid, quercetin, structural genomics consortium, sgc, branched-chain amino acid catabolism, disease mutation, mitochondrion, transit peptide
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion : Q6NVY1
• Total number of polymer chains: 1
• Total formula weight: 41484.86

Authors

Pilka, E.S.,Phillips, C.,King, O.N.F.,Guo, K.,von Delft, F.,Pike, A.C.W.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2007-12-19, release date: 2008-01-08, Last modification date: 2017-10-25)

• Primary citation: Pilka, E.S.,Phillips, C.,King, O.N.F.,Guo, K.,von Delft, F.,Pike, A.C.W.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Oppermann, U.; Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)