3BPM
Crystal Structure of Falcipain-3 with Its inhibitor, Leupeptin
Summary for 3BPM
| Entry DOI | 10.2210/pdb3bpm/pdb |
| Related | 1AIM 1YVB 2GHU 3BPF |
| Related PRD ID | PRD_000216 |
| Descriptor | Cysteine protease falcipain-3, Leupeptin, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | falcipain, malaria, cysteine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Plasmodium falciparum More |
| Total number of polymer chains | 4 |
| Total formula weight | 56090.63 |
| Authors | kerr, I.D.,Lee, J.H.,Brinen, L.S. (deposition date: 2007-12-18, release date: 2008-12-30, Last modification date: 2023-08-30) |
| Primary citation | Kerr, I.D.,Lee, J.H.,Pandey, K.C.,Harrison, A.,Sajid, M.,Rosenthal, P.J.,Brinen, L.S. Structures of falcipain-2 and falcipain-3 bound to small molecule inhibitors: implications for substrate specificity. J.Med.Chem., 52:852-857, 2009 Cited by PubMed: 19128015DOI: 10.1021/jm8013663 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report
