3BNY
Crystal structure of aristolochene synthase complexed with 2-fluorofarnesyl diphosphate (2F-FPP)
Summary for 3BNY
Entry DOI | 10.2210/pdb3bny/pdb |
Related | 2E4O 2OA6 3BNX |
Descriptor | Aristolochene synthase, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | sesquiterpene cyclase, isoprenoid, farnesyl diphosphate, magnesium, cyclization, lyase |
Biological source | Aspergillus terreus |
Total number of polymer chains | 4 |
Total formula weight | 147990.29 |
Authors | Shishova, E.Y.,Christianson, D.W. (deposition date: 2007-12-14, release date: 2008-03-25, Last modification date: 2023-08-30) |
Primary citation | Shishova, E.Y.,Yu, F.,Miller, D.J.,Faraldos, J.A.,Zhao, Y.,Coates, R.M.,Allemann, R.K.,Cane, D.E.,Christianson, D.W. X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis J.Biol.Chem., 283:15431-15439, 2008 Cited by PubMed: 18385128DOI: 10.1074/jbc.M800659200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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