3BH8

Crystal Structure of RQA_M Phosphopeptide Bound to HUMAN Class I MHC HLA-A2

Summary for 3BH8

Entry DOI	10.2210/pdb3bh8/pdb
Related	3BGM 3BH9 3BHA 3BHB
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, decameric peptide from Lymphocyte-specific protein 1, ... (5 entities in total)
Functional Keywords	phosphoserine, phosphopeptide, mhc, hla-a2, anchor residue, tumor antigen, glycoprotein, host-virus interaction, immune response, mhc i, polymorphism, transmembrane, ubl conjugation, immunoglobulin domain, phosphoprotein, immune system
Biological source	Homo sapiens (Human) More
Cellular location	Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 Cell membrane; Peripheral membrane protein; Cytoplasmic side: P33241
Total number of polymer chains	3
Total formula weight	44940.87
Authors	Mohammed, F.,Cobbold, M.,Zarling, A.L.,Salim, M.,Barrett-Wilt, G.A.,Shabanowitz, J.,Hunt, D.F.,Engelhard, V.H.,Willcox, B.E. (deposition date: 2007-11-28, release date: 2008-10-21, Last modification date: 2011-07-13)
Primary citation	Mohammed, F.,Cobbold, M.,Zarling, A.L.,Salim, M.,Barrett-Wilt, G.A.,Shabanowitz, J.,Hunt, D.F.,Engelhard, V.H.,Willcox, B.E. Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self Nat.Immunol., 9:1236-1243, 2008 Cited by PubMed: 18836451 DOI: 10.1038/ni.1660 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation