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3BAY

N298S Variant of Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose

Summary for 3BAY
Entry DOI10.2210/pdb3bay/pdb
Related1BSI 1CPU 1HNY 2QMK 2QV4 3BAI 3BAJ 3BAK 3BAW 3BAX
DescriptorPancreatic alpha-amylase, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, ... (6 entities in total)
Functional Keywordsamylase, anion acitvation, chloride, nitrate, acarbose, human, pancreatic, enzyme, hydrolase, transglycosylation, carbohydrate metabolism, glycoprotein, glycosidase, metal-binding, pyrrolidone carboxylic acid, secreted
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight57035.32
Authors
Fredriksen, J.R.,Maurus, R.,Brayer, G.D. (deposition date: 2007-11-08, release date: 2008-03-25, Last modification date: 2023-08-30)
Primary citationMaurus, R.,Begum, A.,Williams, L.K.,Fredriksen, J.R.,Zhang, R.,Withers, S.G.,Brayer, G.D.
Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47:3332-3344, 2008
Cited by
PubMed: 18284212
DOI: 10.1021/bi701652t
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.99 Å)
Structure validation

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