3B3A

Structure of E163K/R145E DJ-1

Summary for 3B3A

• Entry DOI: 10.2210/pdb3b3a/pdb
• Related: 2B36 2B38 2RK3 2RK4 2RK6
• Descriptor: Protein DJ-1, CHLORIDE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: parkinson's disease, thij, pfpi, chaperone, cytoplasm, disease mutation, nucleus, oncogene, oxidation, parkinson disease, phosphorylation, polymorphism, ubl conjugation
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q99497
• Total number of polymer chains: 1
• Total formula weight: 20392.97

Authors

Lakshminarasimhan, M.,Maldonado, M.T.,Zhou, W.,Fink, A.L.,Wilson, M.A. (deposition date: 2007-10-19, release date: 2008-01-15, Last modification date: 2023-08-30)

• Primary citation: Lakshminarasimhan, M.,Maldonado, M.T.,Zhou, W.,Fink, A.L.,Wilson, M.A.; Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1.; Biochemistry, 47:1381-1392, 2008; PubMed: 18181649; DOI: 10.1021/bi701189c

Experimental method

X-RAY DIFFRACTION (1.5 Å)