3B2D

Crystal structure of human RP105/MD-1 complex

Summary for 3B2D

• Entry DOI: 10.2210/pdb3b2d/pdb
• Descriptor: CD180 antigen, Lymphocyte antigen 86, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: protein-protein complex, leucine rich repeat md-2 related lipid recognition, receptor innate immunity, glycosylation, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Single-pass type I membrane protein: Q99467; Secreted, extracellular space: O95711
• Total number of polymer chains: 4
• Total formula weight: 171036.23

Authors

Ohto, U.,Shimizu, T. (deposition date: 2011-07-29, release date: 2011-11-09, Last modification date: 2020-07-29)

• Primary citation: Ohto, U.,Miyake, K.,Shimizu, T.; Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.; J.Mol.Biol., 413:815-825, 2011; PubMed: 21959264; DOI: 10.1016/j.jmb.2011.09.020

Experimental method

X-RAY DIFFRACTION (2.8 Å)