3AVR

Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II)

Summary for 3AVR

• Entry DOI: 10.2210/pdb3avr/pdb
• Related: 3AVS
• Descriptor: Lysine-specific demethylase 6A, Histone H3, N-OXALYLGLYCINE, ... (8 entities in total)
• Functional Keywords: cupin superfamily, tri/dimethyllysine demethylase, oxidoreductase-structural protein complex, oxidoreductase/structural protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus (Probable): O15550
• Total number of polymer chains: 2
• Total formula weight: 63478.89

Authors

Sengoku, T.,Yokoyama, S. (deposition date: 2011-03-07, release date: 2011-10-19, Last modification date: 2023-11-01)

• Primary citation: Sengoku, T.,Yokoyama, S.; Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A; Genes Dev., 25:2266-2277, 2011; PubMed: 22002947; DOI: 10.1101/gad.172296.111

Experimental method

X-RAY DIFFRACTION (1.803 Å)