3AV5
Crystal structure of mouse DNA methyltransferase 1 with AdoHcy
Summary for 3AV5
| Entry DOI | 10.2210/pdb3av5/pdb |
| Related | 3AV4 3AV6 |
| Descriptor | DNA (cytosine-5)-methyltransferase 1, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total) |
| Functional Keywords | cxxc-type zinc finger/c5-methyltransferase family, methylates cpg residues, preferentially methylates hemimethylated dna, dna binding, hemi-methylation, nucleus, transferase |
| Biological source | Mus musculus (mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 151442.52 |
| Authors | Takeshita, K.,Suetake, I.,Yamashita, E.,Suga, M.,Narita, H.,Nakagawa, A.,Tajima, S. (deposition date: 2011-02-22, release date: 2011-05-04, Last modification date: 2023-11-01) |
| Primary citation | Takeshita, K.,Suetake, I.,Yamashita, E.,Suga, M.,Narita, H.,Nakagawa, A.,Tajima, S. Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108:9055-9059, 2011 Cited by PubMed: 21518897DOI: 10.1073/pnas.1019629108 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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