3ANS
Human soluble epoxide hydrolase in complex with a synthetic inhibitor
Summary for 3ANS
Entry DOI | 10.2210/pdb3ans/pdb |
Related | 3ANT |
Descriptor | Epoxide hydrolase 2, 4-cyano-N-[(1S,2R)-2-phenylcyclopropyl]benzamide (3 entities in total) |
Functional Keywords | hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P34913 |
Total number of polymer chains | 2 |
Total formula weight | 77817.46 |
Authors | Chiyo, N.,Ishii, T.,Hourai, S.,Yanagi, K. (deposition date: 2010-09-08, release date: 2011-01-19, Last modification date: 2023-11-01) |
Primary citation | Tanaka, D.,Tsuda, Y.,Shiyama, T.,Nishimura, T.,Chiyo, N.,Tominaga, Y.,Sawada, N.,Mimoto, T.,Kusunose, N. A practical use of ligand efficiency indices out of the fragment-based approach: ligand efficiency-guided lead identification of soluble epoxide hydrolase inhibitors J.Med.Chem., 54:851-857, 2011 Cited by PubMed: 21192659DOI: 10.1021/jm101273e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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