3A4D

Crystal structure of Human Transthyretin (wild-type)

Summary for 3A4D

Entry DOI	10.2210/pdb3a4d/pdb
Related	3A4E 3A4F
Descriptor	Transthyretin, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	beta barrel, amyloid, amyloidosis, disease mutation, gamma-carboxyglutamic acid, glycoprotein, hormone, neuropathy, retinol-binding, secreted, thyroid hormone, transport, vitamin a, transport protein, thyroxine
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	28023.13
Authors	Miyata, M. (deposition date: 2009-07-06, release date: 2009-12-22, Last modification date: 2023-11-01)
Primary citation	Miyata, M.,Sato, T.,Mizuguchi, M.,Nakamura, T.,Ikemizu, S.,Nabeshima, Y.,Susuki, S.,Suwa, Y.,Morioka, H.,Ando, Y.,Suico, M.A.,Shuto, T.,Koga, T.,Yamagata, Y.,Kai, H. Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding Biochemistry, 2009 Cited by PubMed: 19950966 DOI: 10.1021/bi901677z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation