381D
BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES
Summary for 381D
Entry DOI | 10.2210/pdb381d/pdb |
Descriptor | DNA (5'-D(*TP*GP*GP*CP*CP*G)-3'), DNA (5'-D(*TP*GP*(G49)P*CP*CP*G)-3'), 2'-BROMO-4'-EPIDAUNORUBICIN, ... (4 entities in total) |
Functional Keywords | right handed dna, double helix, complexed with drug, modified, mismatched, dna |
Total number of polymer chains | 2 |
Total formula weight | 4877.29 |
Authors | Dutta, R.,Gao, Y.-G.,Priebe, W.,Wang, A.H.-J. (deposition date: 1998-02-18, release date: 1998-07-13, Last modification date: 2024-02-21) |
Primary citation | Dutta, R.,Gao, Y.G.,Priebe, W.,Wang, A.H. Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res., 26:3001-3005, 1998 Cited by PubMed: 9611247DOI: 10.1093/nar/26.12.3001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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