2ZW3

Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution

Summary for 2ZW3

Entry DOI	10.2210/pdb2zw3/pdb
Descriptor	Gap junction beta-2 protein (1 entity in total)
Functional Keywords	ion channel, alpha helical membrane channel, two double layered lipid spanning, cellular adhesion, cell junction, cell membrane, deafness, disease mutation, ectodermal dysplasia, gap junction, hearing, ichthyosis, membrane, non-syndromic deafness, palmoplantar keratoderma, polymorphism, transmembrane, cell adhesion
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Multi-pass membrane protein: P29033
Total number of polymer chains	6
Total formula weight	157482.44
Authors	Maeda, S.,Nakagawa, S.,Suga, M.,Yamashita, E.,Oshima, A.,Fujiyoshi, Y.,Tsukihara, T. (deposition date: 2008-12-01, release date: 2009-04-07, Last modification date: 2011-07-13)
Primary citation	Maeda, S.,Nakagawa, S.,Suga, M.,Yamashita, E.,Oshima, A.,Fujiyoshi, Y.,Tsukihara, T. Structure of the connexin 26 gap junction channel at 3.5 A resolution Nature, 458:597-602, 2009 Cited by PubMed: 19340074 DOI: 10.1038/nature07869 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation