2ZV9
Lyn Tyrosine Kinase Domain-PP2 complex
Summary for 2ZV9
Entry DOI | 10.2210/pdb2zv9/pdb |
Related | 2ZV7 2ZV8 2ZVA |
Descriptor | Tyrosine-protein kinase Lyn, 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE (3 entities in total) |
Functional Keywords | lyn kinase pp2, alternative splicing, atp-binding, kinase, lipoprotein, myristate, nucleotide-binding, palmitate, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, transferase, tyrosine-protein kinase |
Biological source | Mus musculus (mouse) |
Cellular location | Cell membrane (By similarity): P25911 |
Total number of polymer chains | 1 |
Total formula weight | 32113.42 |
Authors | Williams, N.K.,Rossjohn, J. (deposition date: 2008-11-04, release date: 2008-11-11, Last modification date: 2023-11-01) |
Primary citation | Williams, N.K.,Lucet, I.S.,Klinken, S.P.,Ingley, E.,Rossjohn, J. Crystal Structures of the Lyn Protein Tyrosine Kinase Domain in Its Apo- and Inhibitor-bound State J.Biol.Chem., 284:284-291, 2009 Cited by PubMed: 18984583DOI: 10.1074/jbc.M807850200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.76 Å) |
Structure validation
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