2ZQ1

Exploring trypsin S3 pocket

Summary for 2ZQ1

• Entry DOI: 10.2210/pdb2zq1/pdb
• Related: 2ZFS 2ZFT 2ZHD 2ZQ2 3BIV
• Related PRD ID: PRD_000587
• Descriptor: Cationic trypsin, CALCIUM ION, SULFATE ION, ... (6 entities in total)
• Functional Keywords: hydrolase inhibitors, digestion, hydrolase, metal-binding, protease, secreted, serine protease, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bos taurus (Bovine)
• Cellular location: Secreted, extracellular space: P00760
• Total number of polymer chains: 1
• Total formula weight: 23938.03

Authors

Brandt, T.,Baum, B.,Heine, A.,Klebe, G. (deposition date: 2008-08-03, release date: 2009-08-04, Last modification date: 2023-11-01)

• Primary citation: Brandt, T.,Holzmann, N.,Muley, L.,Khayat, M.,Wegscheid-Gerlach, C.,Baum, B.,Heine, A.,Hangauer, D.,Klebe, G.; Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties; J.Mol.Biol., 405:1170-1187, 2011; PubMed: 21111747; DOI: 10.1016/j.jmb.2010.11.038

Experimental method

X-RAY DIFFRACTION (1.68 Å)