2ZOQ

Structural dissection of human mitogen-activated kinase ERK1

Summary for 2ZOQ

Entry DOI	10.2210/pdb2zoq/pdb
Descriptor	Mitogen-activated protein kinase 3, SULFATE ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	serine/threonine kinase, erk1, acetylation, atp-binding, cell cycle, host-virus interaction, nucleotide-binding, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	88077.91
Authors	Kinoshita, T.,Tada, T.,Nakae, S.,Yoshida, I. (deposition date: 2008-06-01, release date: 2009-04-07, Last modification date: 2023-11-15)
Primary citation	Kinoshita, T.,Yoshida, I.,Nakae, S.,Okita, K.,Gouda, M.,Matsubara, M.,Yokota, K.,Ishiguro, H.,Tada, T. Crystal structure of human mono-phosphorylated ERK1 at Tyr204 Biochem.Biophys.Res.Commun., 377:1123-1127, 2008 Cited by PubMed: 18983981 DOI: 10.1016/j.bbrc.2008.10.127 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.39 Å)

Structure validation